The lipid phosphatase SHIP2 controls insulin sensitivity (vol 409, pg 92, 2001)

被引:22
作者
Clément, S
Krause, U
Desmedt, F
Tanti, JF
Behrends, J
Pesesse, X
Sasaki, T
Penninger, J
Doherty, M
Malaisse, W
Dumont, JE
Le Marchand-Brustel, Y
Erneux, C
Hue, L
Schurmans, S
机构
关键词
D O I
10.1038/nature03003
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Nature 409, 92–96 (2001). In this Letter, we investigated the production and the phenotypic characterization of a SHIP2 (SH2 domain containing inositol phosphate 5-phosphatase type 2, or Inppl1) knockout mice. Total or partial loss of SHIP2 enzyme in these mice resulted in an increased insulin sensitivity.
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页码:878 / 878
页数:1
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[1]   The lipid phosphatase SHIP2 controls insulin sensitivity [J].
Clément, S ;
Krause, U ;
Desmedt, F ;
Tanti, JF ;
Behrends, J ;
Pesesse, X ;
Sasaki, T ;
Penninger, J ;
Doherty, M ;
Malaisse, W ;
Dumont, JE ;
Le Marchand-Brustel, Y ;
Erneux, C ;
Hue, L ;
Schurmans, S .
NATURE, 2001, 409 (6816) :92-97