Two-component systems in Pseudomonas aeruginosa:: why so many?

被引：201

作者：

Rodrigue, A

Quentin, Y

Lazdunski, A

Méjean, V

Foglino, M

机构：

[1] CNRS, Lab Ingn Syst Macromol, F-13402 Marseille, France

[2] CNRS, Chim Bacterienne Lab, F-13402 Marseille, France

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 11期

关键词：

D O I：

10.1016/S0966-842X(00)01833-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Screening the Pseudomonas aeruginosa genome has led to the identification of the highest number of putative genes encoding two-component regulatory systems of all bacterial genomes sequenced to date (64 and 63 encoding response regulators and histidine kinases, respectively), Sixteen atypical kinases, among them 11 devoid of an Hpt domain, and three independent Hpt modules were retrieved. These data suggest that P. aeruginosa possesses complex control strategies with which to respond to environmental challenges.

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页码：498 / 504

页数：7

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