PCOS: an ovarian disorder that leads to dysregulation in the hypothalamic-pituitary-adrenal axis?

被引：43

作者：

Doi, SAR

Towers, PA

Scott, CJ

Al-Shoumer, KAS

机构：

[1] Kuwait Univ, Mubarak Al Kabeer Hosp, Div Endocrinol, Shuwaikh 70459, Kuwait

[2] Kuwait Univ, Fac Med, Dept Med, Shuwaikh 70459, Kuwait

[3] Charles Sturt Univ, Sch Biomed Sci, Wagga Wagga, NSW, Australia

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2005年 / 118卷 / 01期

关键词：

polycystic ovary syndrome; ovarian disorder; hypothalamic-pituitary-adrenal axis;

D O I：

10.1016/j.ejogrb.2004.06.024

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This review focuses on the role of the ovaries in the pathogenesis of the polycystic ovarian syndrome. In particular, the failure of follicular development, hypothalamo-pituitary dysregulation, alterations in adrenal steroid output and derangement of intermediary metabolism are discussed in the context of the ovaries. It is concluded that the central and adrenal alterations associated with PCOS are unlikely to be primary but rather are secondary to the events within the ovary. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

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页码：4 / 16

页数：13

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