Characterisation of small molecules diffusion in hydrogel-membrane liquid-core capsules

被引:49
作者
Dembczynski, R [1 ]
Jankowski, T [1 ]
机构
[1] Agr Univ Poznan, Dept Biotechnol, PL-60623 Poznan, Poland
关键词
alginate; diffusion; glucose; hydrogel capsule; immobilisation; mass transfer;
D O I
10.1016/S1369-703X(00)00070-X
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The overall diffusion coefficients for several low molecular weight solutes, such as glucose, fructose, sucrose, lactose, and vitamin B-12 have been determined in Ca-alginate membrane liquid-core capsules using the unsteady-state method following the release of solutes from the capsules to a well-stirred solution of limited volume. The diffusion coefficients obtained for saccharides were 5-20% lower than the corresponding diffusivity in water while for vitamin B-12 about 50% that of water. The diffusion coefficients of the investigated capsules were not influenced by the change in alginate concentration in the capsule membrane from 0.5 to 1.0%. Lower diffusivities and higher deviations from the diffusivity in water were obtained for higher molecular weight solutes. (C) 2000 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:41 / 44
页数:4
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