Neurobiology - Fear thou not

被引：5

作者：

Dudai, Y ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Neurobiol, IL-76100 Rehovot, Israel

来源：

NATURE | 2003年 / 421卷 / 6921期

关键词：

D O I：

10.1038/421325a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mice lacking a certain neurotransmitter receptor have trouble forgetting scary experiences. This finding uncovers a fear-regulating feedback loop in the brain that might be at work in humans, too.

引用

页码：325 / 327

页数：3

共 8 条

[1]

AGGLETON JP, 2000, ANYGDALA FUNCTIONAL

[2] Is the amygdala a locus of "conditioned fear"? Some questions and caveats [J].

Cahill, L ;

Weinberger, NM ;

Roozendaal, B ;

McGaugh, JL .

NEURON, 1999, 23 (02) :227-228

[3] Fear memory formation involves p190 RhoGAP and ROCK proteins through a GRB2-mediated complex [J].

Lamprecht, R ;

Farb, CR ;

LeDoux, JE .

NEURON, 2002, 36 (04) :727-738

[4]

LeDoux J. E., 1996, EMOTIONAL BRAIN MYST

[5] N-methyl-D-aspartate receptors in the basolateral amygdala are required for both acquisition and expression of conditional fear in rats [J].

Maren, S ;

Aharonov, G ;

Stote, DL ;

Fanselow, MS .

BEHAVIORAL NEUROSCIENCE, 1996, 110 (06) :1365-1374

[6]

Ressler KJ, 2002, J NEUROSCI, V22, P7892

[7] Fear conditioning induces associative long-term potentiation in the amygdala [J].

Rogan, MT ;

Staubli, UV ;

LeDoux, JE .

NATURE, 1997, 390 (6660) :604-607

[8]

SMUNYATSKY GP, 2002, CELL, V111, P905

← 1 →