Assignment of human plasma methylumbelliferyl-tetra-N-acetylchitote hydrolase or chitinase to chromosome 1q by a linkage study

被引：21

作者：

Eiberg, H ^{[1
]}

DenTandt, WR ^{[1
]}

机构：

[1] UNIV INSTELLING ANTWERP,FAC MED,B-2610 WILRIJK,BELGIUM

来源：

HUMAN GENETICS | 1997年 / 101卷 / 02期

关键词：

D O I：

10.1007/s004390050615

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase or chitinase (CHIT) might play a role in degrading the chitin wall of some microorganisms. In about 6% of Caucasian people the enzyme shows pseudodeficiency (defined as very low activity without apparent symptoms). We have mapped this locus by linkage analysis to the marker D1S306 (z = 4.00 at theta(M=F) = 0.0) on chromosome Iq between the flanking markers D1S191 and D1S245 in the area of 1q31-1qter.

引用

页码：205 / 207

页数：3

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