Molecular shaping of the beak

被引:205
作者
Wu, P [1 ]
Jiang, TX [1 ]
Suksaweang, S [1 ]
Widelitz, RB [1 ]
Chuong, CM [1 ]
机构
[1] Univ So Calif, Dept Pathol, Keck Sch Med, Los Angeles, CA 90033 USA
关键词
D O I
10.1126/science.1098109
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Beak shape is a classic example of evolutionary diversification. Beak development in chicken and duck was used to examine morphological variations among avian species. There is only one proliferative zone in the frontonasal mass of chickens, but two in ducks. These growth zones are associated with bone morphogenetic protein 4 (BMP4) activity. By "tinkering" with BMP4 in beak prominences, the shapes of the chicken beak can be modulated.
引用
收藏
页码:1465 / 1466
页数:2
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