p53: a heavily dictated dictator of life and death

被引：57

作者：

Lu, X ^{[1
]}

机构：

[1] Ludwig Inst Canc Res, London W1W 7BS, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2005年 / 15卷 / 01期

关键词：

D O I：

10.1016/j.gde.2004.12.008

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In 2003, a p53-expressing adenovirus was approved as a cancer therapy drug in China. Consequently, there has been a surge in the need to understand the regulation of wild type p53 function in vivo. The majority of the progress made during the past two years has focused on the cellular factors and post-translational modifications that regulate the expression levels and activities of p53 in response to stress signals.

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页码：27 / 33

页数：7

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