Resistance mutations in subtype CHIV type 1 isolates from Indian patients of mumbai receiving NRTIs plus NNRTIs and experiencing a treatment failure: Resistance to AR

被引：42

作者：

Deshpande, Alaka

Jauvin, Valerie

Magnin, Noel

Pinson, Patricia

Faure, Muriel

Masquelier, Bernard

Aurillac-Lavignolle, Valerie

Fleury, Herve J. ^{[1
]}

机构：

[1] Univ Bordeaux 2, Lab Virol EA 2968, F-33076 Bordeaux, France

[2] Grant Med Coll, Bombay, Maharashtra, India

[3] Sir JJ Hosp, Bombay, Maharashtra, India

[4] INSERM, U593, Bordeaux, France

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 2007年 / 23卷 / 02期

关键词：

D O I：

10.1089/aid.2006.0183

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We present here the first data available on resistance to nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) in India. In these subtype C isolates, we have observed most of the mutations noted in reverse transcriptase (RT) for subtype B with some additional substitutions ( at positions 98, 203, 208, and 221) that will warrant attention in the algorithms used.

引用

页码：335 / 340

页数：6

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