Recent advances in asymmetric organocatalytic 1,4-conjugate additions

被引：1128

作者：

Tsogoeva, Svetlana B. ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Organ Chem, D-91054 Erlangen, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 2007卷 / 11期

关键词：

1,4-conjugate addition; Michael addition; asymmetric reactions; chiral amines; multicomponent reactions; organocatalysis;

D O I：

10.1002/ejoc.200600653

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Recent progress in the field of asymmetric organocatalytic 1,4-conjugate addition reactions, regarded as belonging among the more synthetically important carbon-carbon bond-forming reactions, is described. The focus is on some recent advances in the following selected reactions: additions of various nucleophiles to alpha,beta-unsaturated cyclic and acyclic enals, enones, vinyl sulfones and nitro olefins, addition of malonates and/or ketones to acyclic enones, or of aldehydes and ketones to vinyl ketones and nitro olefins, together with some multicomponent domino reactions. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007).

引用

页码：1701 / 1716

页数：16

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