Pharmacogenetics of the alcohol dehydrogenase system

被引：41

作者：

Jörnvall, H

Höög, JO

Persson, B

Parés, X

机构：

[1] Karolinska Inst, Dept Med Biochem & Biophys, SE-17177 Stockholm, Sweden

[2] Stockholm Bioinformat Ctr, Stockholm, Sweden

[3] Univ Autonoma Barcelona, Dept Biochem & Mol Biol, Bellaterra, Barcelona, Spain

来源：

PHARMACOLOGY | 2000年 / 61卷 / 03期

关键词：

alcohol dehydrogenase isozymes; evolution; pharmacogenetics; biochemistry; structure; regulation; toxicology;

D O I：

10.1159/000028399

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Alcohol dehydrogenase (ADH) constitutes a complex enzyme system with different forms and extensive multiplicity. A combination of constant and variable properties regarding function, multiplicity and structure of ADH is highlighted for the human system and extended to ADH forms in general. Future perspectives suggest continued studies in specific directions for distinction of metabolic, regulatory and pharmacogenetic roles of ADH, Copyright(C)2000S.KargerAG.Basel.

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页码：184 / 191

页数：8

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