Detection of JC virus in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy but not in CSF samples from patients with herpes simplex encephalitis, enteroviral meningitis, or multiple sclerosis

被引：24

作者：

Bogdanovic, G

Priftakis, P

Hammarin, AL

Söderström, M

Samuelson, A

Lewensohn-Fuchs, I

Dalianis, T ^{[1
]}

机构：

[1] Huddinge Univ Hosp, Karolinska Inst, Div Clin Virol F68, Dept Immunol Microbiol Pathol & Infect Dis, S-14186 Huddinge, Sweden

[2] Huddinge Univ Hosp, Karolinska Inst, Dept Ophthalmol & Neurol, S-14186 Huddinge, Sweden

[3] Swedish Inst Infect Dis Control, Dept Virol, Stockholm, Sweden

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1998年 / 36卷 / 04期

关键词：

D O I：

10.1128/JCM.36.4.1137-1138.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

JC virus (JCV) DNA was detected in cerebrospinal fluid (CSF) samples from patients with progressive multifocal leukoencephalopathy (PML) but not in CSF samples from patients with herpes simplex encephalitis, enteroviral meningitis, or multiple sclerosis. This suggests that inflammatory processes in the brain do not necessarily reactivate JCV, which further supports the proposal that the presence of JCV DNA in the CSF is diagnostic for PML.

引用

页码：1137 / 1138

页数：2

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