A unique and highly facile method for synthesising disulfide linked neoglycoconjugates: a new approach for remodelling of peptides and proteins

被引：55

作者：

Macindoe, WM ^{[1
]}

van Oijen, AH ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 07期

关键词：

D O I：

10.1039/a708701b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An asymmetric disulfide linkage, formed by conjugation of a 5-nitropyridine-2-sulfenyl activated thioglycoside and a protein or pre-assembled peptide sequence, represents a good structural mimic of natural asparagine glycosylation.

引用

页码：847 / +

页数：2

共 20 条

[1]

Carayannopoulos Leon, 1993, P283

[2]

CHANG Y, 1988, SEMIN ULTRASOUND CT, V9, P343

[3] A NOVEL METHOD FOR THE SPECIFIC GLYCOSYLATION OF PROTEINS [J].

DAVIS, NJ ;

FLITSCH, SL .

TETRAHEDRON LETTERS, 1991, 32 (46) :6793-6796

[4] CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF A HUMAN FC FRAGMENT AND ITS COMPLEX WITH FRAGMENT-B OF PROTEIN-A FROM STAPHYLOCOCCUS-AUREUS AT 2.9-A AND 2.8-A RESOLUTION [J].

DEISENHOFER, J .

BIOCHEMISTRY, 1981, 20 (09) :2361-2370

[5] TISSUE SULFHYDRYL GROUPS [J].

ELLMAN, GL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77

[6] STEREOCHEMISTRY OF THE N-GLYCOSYLATION SITES IN GLYCOPROTEINS [J].

IMBERTY, A ;

PEREZ, S .

PROTEIN ENGINEERING, 1995, 8 (07) :699-709

[7] GLYCOSYLATION OF RECOMBINANT PROTEINS - PROBLEMS AND PROSPECTS [J].

JENKINS, N ;

CURLING, EMA .

ENZYME AND MICROBIAL TECHNOLOGY, 1994, 16 (05) :354-364

[8]

KNIGHT P, 1989, BIO-TECHNOL, V7, P35, DOI 10.1038/nbt0189-35

[9]

KOBATA A, 1992, STRUCTURE BIOSYNTHES, P1

[10] In vitro glycosylation of proteins: An enzymatic approach [J].

MeynialSalles, I ;

Combes, D .

JOURNAL OF BIOTECHNOLOGY, 1996, 46 (01) :1-14

← 1 2 →