Development of a bioassay employing the desert locust (Schistocerca gregaria) for the detection of saxitoxin and related compounds in cyanobacteria and shellfish

被引：13

作者：

Mcelhiney, J

Lawton, LA

Edwards, C

Gallacher, S

机构：

[1] Robert Gordon Univ, Sch Appl Sci, Aberdeen AB25 1HG, Scotland

[2] Biotage UK Ltd, Hertford, England

[3] Dept Agr & Fisheries Scotland, Marine Lab, Aberdeen AB9 8DB, Scotland

来源：

TOXICON | 1998年 / 36卷 / 02期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1016/S0041-0101(97)00077-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Monitoring paralytic shellfish toxins (PST) in shellfish and freshwater cyanobacteria is largely dependent on the mouse bioassay. An alternative assay was devised using the desert locust Schistocerca gregaria. The bioassay successfully identified the optimum extraction procedure for PST from cyanobacterial cells and was also suitable for screening acid extracts of shellfish flesh. These results demonstrate the potential of the locust bioassay for the routine screening of PST in a range of sample matrices. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：417 / 420

页数：4

共 10 条

[1]

*AOAC, 1990, OFF METH AN, V2, P881

[2] RECENT STUDIES ON PARALYTIC SHELLFISH POISON IN JAPAN [J].