Hole transfer rates in A-form DNA/2′-OMeRNA hybrid

被引:16
作者
Kawai, Kiyohiko [1 ]
Osakada, Yasuko [1 ]
Sugimoto, Akira [1 ]
Fujitsuka, Mamoru [1 ]
Majima, Tetsuro [1 ]
机构
[1] Osaka Univ, Inst Sci & Ind Res SANKEN, Osaka 5670047, Japan
关键词
charge transfer; DNA structures; DNA; RNA; transient absorption;
D O I
10.1002/chem.200601210
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The hole transfer rates in the DNA/DNA B-form duplex and DNA/2'-OMeRNA A-form duplex were measured which occurred in the time range of approximate to 100 mu s. The hole transfer rates in the A-form duplexes were slower and more strongly dependent on the temperature compared to those in the B-form duplexes, suggesting that the A-form is more rigid than the B-form duplex in this time scale.
引用
收藏
页码:2386 / 2391
页数:6
相关论文
共 46 条
[1]  
ARNOTT S, 1986, J MOL BIOL, V188, P631, DOI 10.1016/S0022-2836(86)80011-0
[2]   Fluctuation-facilitated charge migration along DNA [J].
Bruinsma, R ;
Grüner, G ;
D'Orsogna, MR ;
Rudnick, J .
PHYSICAL REVIEW LETTERS, 2000, 85 (20) :4393-4396
[3]   STRUCTURE AND ACID-BASE PROPERTIES OF ONE-ELECTRON-OXIDIZED DEOXYGUANOSINE, GUANOSINE, AND 1-METHYLGUANOSINE [J].
CANDEIAS, LP ;
STEENKEN, S .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (03) :1094-1099
[4]   Antisense starts making more sense [J].
Carmichael, GG .
NATURE BIOTECHNOLOGY, 2003, 21 (04) :371-372
[5]   Structure-function correlations of the insulin-linked polymorphic region [J].
Catasti, P ;
Chen, X ;
Moyzis, RK ;
Bradbury, EM ;
Gupta, G .
JOURNAL OF MOLECULAR BIOLOGY, 1996, 264 (03) :534-545
[6]   Distance-dependent activation energies for hole injection from protonated 9-amino-6-chloro-2-methoxyacridine into duplex DNA [J].
Davis, WB ;
Hess, S ;
Naydenova, I ;
Haselsberger, R ;
Ogrodnik, A ;
Newton, MD ;
Michel-Beyerle, ME .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (11) :2422-2423
[7]   Direct observation of hole transfer through DNA by hopping between adenine bases and by tunnelling [J].
Giese, B ;
Amaudrut, J ;
Köhler, AK ;
Spormann, M ;
Wessely, S .
NATURE, 2001, 412 (6844) :318-320
[8]   Flexibility of RNA [J].
Hagerman, PJ .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1997, 26 :139-156
[9]   On the apparently anomalous distance dependence of charge-transfer rates in 9-amino-6-chloro-2-methoxyacridine-modified DNA [J].
Hess, S ;
Götz, M ;
Davis, WB ;
Michel-Beyerle, ME .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (41) :10046-10055
[10]   Kinetics of transient end-to-end contact of single-stranded DNAs [J].
Kawai, K ;
Yoshida, H ;
Sugimoto, A ;
Fujitsuka, M ;
Majima, T .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (38) :13232-13237