Biosensors for clinical diagnostics industry

被引:201
作者
Malhotra, BD [1 ]
Chaubey, A [1 ]
机构
[1] Natl Phys Lab, Biomol Elect & Conducting Polymer Res Grp, New Delhi 110012, India
关键词
biosensors; immobilization; cross-linking; microencapsulation;
D O I
10.1016/S0925-4005(03)00075-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
There is an urgent need in the medical diagnostics laboratories for accurate, fast and inexpensive devices, which can be routinely used. The reliable and accurate information on the desired biochemical parameters is an essential prerequisite for effective healthcare. In this context, biosensors are considered to provide viable solutions to the problems posed by the contemporary healthcare industry. This is because these biosensing devices offer considerable advantages, such as specificity, small size faster response and cost. It is anticipated that these bioanalytical tools can be used for frequent measurements of metabolites, blood cations and gases, etc. In this paper, an attempt has been made to highlight some of the trends that rule the research and developments of some of the important biosensors that are likely to accelerate the growth of clinical diagnostics industry. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:117 / 127
页数:11
相关论文
共 107 条
[1]   POLYPYRROLE-BASED POTENTIOMETRIC BIOSENSOR FOR UREA .1. INCORPORATION OF UREASE [J].
ADELOJU, SB ;
SHAW, SJ ;
WALLACE, GG .
ANALYTICA CHIMICA ACTA, 1993, 281 (03) :611-620
[2]  
BLAEDEL WJ, 1964, ADVANCES ANALYTICAL, V3, P105
[3]   Development of amperometric and microgravimetric immunosensors and reversible immunosensors using antigen and photoisomerizable antigen monolayer electrodes [J].
Blonder, R ;
Levi, S ;
Tao, GL ;
BenDov, I ;
Willner, I .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (43) :10467-10478
[4]  
BOWERS LS, 1976, ANAL CHEM, V48, P545
[5]   Nanostructured carbon fiber disk electrodes for sensitive determinations of adenosine and uric acid [J].
Brajter-Toth, A ;
Abou El-Nour, K ;
Cavalheiro, ET ;
Bravo, R .
ANALYTICAL CHEMISTRY, 2000, 72 (07) :1576-1584
[6]   Possibilities and limitations in miniaturized sensor design for uric acid [J].
Bravo, R ;
Hsueh, C ;
Jaramillo, A ;
Brajter-Toth, A .
ANALYST, 1998, 123 (07) :1625-1630
[7]  
BRIGHT FV, 1998, ANAL PRACTICAL APPRO, pCH10
[8]   AN IMPROVED VOLTAMMETRIC METHOD FOR THE DETERMINATION OF TRACE AMOUNTS OF URIC-ACID WITH ELECTROCHEMICALLY PRETREATED CARBON-PASTE ELECTRODES [J].
CAI, XH ;
KALCHER, K ;
NEUHOLD, C ;
OGOREVC, B .
TALANTA, 1994, 41 (03) :407-413
[9]  
CASS AEG, 1995, ENCY MOL BIOL MOL ME, V1, P177
[10]   Mediated biosensors [J].
Chaubey, A ;
Malhotra, BD .
BIOSENSORS & BIOELECTRONICS, 2002, 17 (6-7) :441-456