The Impact of Ulcerative Colitis on Patients' Lives Compared to Other Chronic Diseases: A Patient Survey

被引：64

作者：

Rubin, David T. ^{[1
]}

Dubinsky, Marla C. ^{[2
]}

Panaccione, Remo ^{[3
]}

Siegel, Corey A. ^{[4
]}

Binion, David G. ^{[5
]}

Kane, Sunanda V. ^{[6
]}

Hopper, Joseph ^{[7
]}

机构：

[1] Univ Chicago, Med Ctr, Dept Med, Gastroenterol Sect, Chicago, IL 60637 USA

[2] Cedars Sinai Med Ctr, Pediat IBD, Los Angeles, CA 90048 USA

[3] Univ Calgary, Div Gastroenterol, Calgary, AB T2N 4N1, Canada

[4] Dartmouth Hitchcock Med Ctr, Sect Gastroenterol & Hepatol, Lebanon, NH 03766 USA

[5] Univ Pittsburgh, Div Gastroenterol & Hepatol, Pittsburgh, PA USA

[6] Mayo Clin, Coll Med, Rochester, MN USA

[7] Versta Res, Evanston, IL USA

来源：

DIGESTIVE DISEASES AND SCIENCES | 2010年 / 55卷 / 04期

关键词：

Chronic disease; Disease burden; Quality of life; Ulcerative colitis; INFLAMMATORY-BOWEL-DISEASE; QUALITY-OF-LIFE; COLORECTAL-CANCER; RISK;

D O I：

10.1007/s10620-009-0953-7

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Purpose This study was designed to identify the impact chronic ulcerative colitis (UC) has on the lives of patients compared to other chronic conditions. Overall, 451 patients with UC, 309 with rheumatoid arthritis, 305 with asthma, and 305 with migraine headaches were recruited in an Internet survey designed to assess a variety of disease-impact indices. Results Patients with UC reported a mean of eight (self-defined) flare-ups in the previous 12 months. Significantly more patients with UC (81%) believed that the quantity of flare-ups they experienced was 'normal', compared to patients with migraine headaches (64%) or asthma (75%). Patients with UC also reported significantly more worry about disease complications (84%), depression (62%), and embarrassment (70%) than patients with the other chronic conditions. Conclusions Compared to patients with other chronic conditions, patients with UC perceive substantially more negative impact upon their lives, especially with regard to the psychological burden.

引用

页码：1044 / 1052

页数：9

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