No influence after various exposure times on the biotransformation rate constants of benzo(a)anthracene in fathead minnow (Pimephales promelas)

被引：8

作者：

de Maagd, PGJ ^{[1
]}

de Poorte, J ^{[1
]}

Opperhuizen, A ^{[1
]}

Sijm, DTHM ^{[1
]}

机构：

[1] Univ Utrecht, Toxicol Res Inst, Environm Chem Grp, NL-3508 TB Utrecht, Netherlands

来源：

AQUATIC TOXICOLOGY | 1998年 / 40卷 / 2-3期

关键词：

benzo(a)anthracene; biotransformation; fish; induction;

D O I：

10.1016/S0166-445X(97)00053-2

中图分类号：

Q17 [水生生物学];

学科分类号：

071004 ;

摘要：

To determine whether or not biotransformation rates of PAH are influenced by induction of enzymes, fathead minnows were exposed to benzo(a)anthracene (B(a)A) in water for various exposure times followed by an elimination period. After exposure for between 5 and 336 h no significant differences between elimination rate constants (mean 1.53 +/- 0.18 d(-1)) were found. From this finding it is concluded that induction of biotransformation of waterborne B(a)A does not occur in fathead minnow. In addition, for B(a)A a bioconcentration factor of 260 1 kg(-1) was found. (C) 1998 Elsevier Science B.V.

引用

页码：157 / 169

页数：13

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