Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

被引:210
作者
Boultwood, J. [1 ]
Perry, J. [1 ]
Pellagatti, A. [1 ]
Fernandez-Mercado, M. [2 ]
Fernandez-Santamaria, C. [1 ]
Calasanz, M. J. [2 ]
Larrayoz, M. J. [2 ]
Garcia-Delgado, M. [2 ]
Giagounidis, A. [3 ]
Malcovati, L. [4 ]
Della Porta, M. G. [4 ]
Jadersten, M. [5 ]
Killick, S. [6 ]
Hellstrom-Lindberg, E. [5 ]
Cazzola, M. [4 ]
Wainscoat, J. S. [1 ]
机构
[1] John Radcliffe Hosp, NDCLS, LRF Mol Haematol Unit, Oxford OX3 9DU, England
[2] Univ Navarra, Dept Genet, E-31080 Pamplona, Spain
[3] St Johannes Hosp, Med Klin 2, Duisburg, Germany
[4] Univ Pavia, Sch Med, Dept Hematol Oncol, Fdn IRCCS Policlin San Matteo, I-27100 Pavia, Italy
[5] Karolinska Inst, Dept Med, Div Hematol, Stockholm, Sweden
[6] Royal Bournemouth Hosp, Dept Haematol, Bournemouth, Dorset, England
关键词
D O I
10.1038/leu.2010.20
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1062 / 1065
页数:5
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