Combinations for cancer prevention

被引：49

作者：

Gupta, RA ^{[1
]}

DuBois, RN

机构：

[1] Vanderbilt Univ, Med Ctr, Dept Med,Vanderbilt Ingram Canc Ctr, Nashville Vet Affairs Med Ctr, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Med Ctr, Dept Cell Biol,Vanderbilt Ingram Canc Ctr, Nashville Vet Affairs Med Ctr, Nashville, TN 37232 USA

来源：

NATURE MEDICINE | 2000年 / 6卷 / 09期

关键词：

D O I：

10.1038/79664

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Combination therapies involving inhibitors of the epidermal growth factor and cyclooxygenase signaling prevent colorectal adenomas in mice. This synergistic effect may be due to the convergance of these two signaling pathways (pages 1024-1028).

引用

页码：974 / 975

页数：2

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