MAEG, an EGF-repeat containing gene, is a new marker associated with dermatome specification and morphogenesis of its derivatives

被引:18
作者
Buchner, G [1 ]
Broccoli, V [1 ]
Bulfone, A [1 ]
Orfanelli, U [1 ]
Gattuso, C [1 ]
Ballabio, A [1 ]
Franco, B [1 ]
机构
[1] Telethon Inst Genet & Med, I-20132 Milan, Italy
关键词
EGF; dermatome; Xp22;
D O I
10.1016/S0925-4773(00)00462-7
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We report on the expression pattern of a novel EGF-containing gene named Maeg. RNA in situ studies indicate that Maeg is first activated during specification of the early lateral dermatome, and continues to be expressed in all the dermatome derivatives as the dermis of the trunk, the hair follicles, and the mesenchyme of the cranio-facial region. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:179 / 182
页数:4
相关论文
共 12 条
[1]   Identification of a new EGF-repeat-containing gene from human Xp22: A candidate for developmental disorders [J].
Buchner, G ;
Orfanelli, U ;
Quaderi, N ;
Bassi, MT ;
Andolfi, G ;
Ballabio, A ;
Franco, B .
GENOMICS, 2000, 65 (01) :16-23
[2]  
Chuong C.M., 1998, MOL BASIS EPITHELIAL
[3]   How is myogenesis initiated in the embryo? [J].
Cossu, G ;
Tajbakhsh, S ;
Buckingham, M .
TRENDS IN GENETICS, 1996, 12 (06) :218-223
[4]   Pax genes and organogenesis [J].
Dahl, E ;
Koseki, H ;
Balling, R .
BIOESSAYS, 1997, 19 (09) :755-765
[5]  
Gossler A, 1998, CURR TOP DEV BIOL, V38, P225
[6]   Isolation and embryonic expression of the novel mouse gene Hic1, the homologue of HIC1, a candidate gene for the Miller-Dieker syndrome [J].
Grimm, C ;
Spörle, R ;
Schmid, TE ;
Adler, ID ;
Adamski, J ;
Schughart, K ;
Graw, J .
HUMAN MOLECULAR GENETICS, 1999, 8 (04) :697-710
[7]  
Houzelstein D, 2000, DEVELOPMENT, V127, P2155
[8]   DERMO-1 - A NOVEL TWIST-RELATED BHLH PROTEIN EXPRESSED IN THE DEVELOPING DERMIS [J].
LI, L ;
CSERJESI, P ;
OLSON, EN .
DEVELOPMENTAL BIOLOGY, 1995, 172 (01) :280-292
[9]  
MAUGER A, 1972, J EMBRYOL EXP MORPH, V28, P313
[10]   EXPRESSION PATTERN OF THE KALLMANN SYNDROME GENE IN THE OLFACTORY SYSTEM SUGGESTS A ROLE IN NEURONAL TARGETING [J].
RUGARLI, EI ;
LUTZ, B ;
KURATANI, SC ;
WAWERSIK, S ;
BORSANI, G ;
BALLABIO, A ;
EICHELE, G .
NATURE GENETICS, 1993, 4 (01) :19-26