Secretion: Dense-core vesicles can kiss-and-run too

被引：58

作者：

Artalejo, CR ^{[1
]}

Elhamdani, A

Palfrey, HC

机构：

[1] Wayne State Univ, Dept Pharmacol, Detroit, MI 48201 USA

[2] Univ Chicago, Dept Pharmacol & Physiol Sci, Chicago, IL 60637 USA

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 02期

关键词：

D O I：

10.1016/S0960-9822(98)70036-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New measurements show that the entire transmitter contents of a dense core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense-core vesicles may, like small synaptic vesicles, undergo immediate recycling.

引用

页码：R62 / R65

页数：4

共 15 条

[1] The exocytotic event in chromaffin cells revealed by patch amperometry [J].

Albillos, A ;

Dernick, G ;

Horstmann, H ;

Almers, W ;

deToledo, GA ;

Lindau, M .

NATURE, 1997, 389 (6650) :509-512

[2] RAPID ENDOCYTOSIS COUPLED TO EXOCYTOSIS IN ADRENAL CHROMAFFIN CELLS INVOLVES CA2+, GTP, AND DYNAMIN BUT NOT CLATHRIN [J].

ARTALEJO, CR ;

HENLEY, JR ;

MCNIVEN, MA ;

PALFREY, CH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (18) :8328-8332

[3] SYNAPTIC TRANSMISSION - KINETICS OF SYNAPTIC-VESICLE RECYCLING [J].

BETZ, WJ ;

WU, LG .

CURRENT BIOLOGY, 1995, 5 (10) :1098-1101

[4] VESICLE HYPOTHESIS OF THE RELEASE OF QUANTA OF ACETYLCHOLINE [J].

CECCARELLI, B ;

HURLBUT, WP .

PHYSIOLOGICAL REVIEWS, 1980, 60 (02) :396-441

[5] DELAY IN VESICLE FUSION REVEALED BY ELECTROCHEMICAL MONITORING OF SINGLE SECRETORY EVENTS IN ADRENAL CHROMAFFIN CELLS [J].

CHOW, RH ;

VONRUDEN, L ;

NEHER, E .

NATURE, 1992, 356 (6364) :60-63

[6] Molecular mechanisms in synaptic vesicle endocytosis and recycling [J].

DeCamilli, P ;

Takei, K .

NEURON, 1996, 16 (03) :481-486

[7] CHROMOGRANIN-A SYNTHESIS AND SECRETION IN CHROMAFFIN CELLS [J].

EIDEN, LE ;

IACANGELO, A ;

HSU, CM ;

HOTCHKISS, AJ ;

BADER, MF ;

AUNIS, D .

JOURNAL OF NEUROCHEMISTRY, 1987, 49 (01) :65-74

[8] Fast steps in exocytosis and endocytosis studied by capacitance measurements in endocrine cells [J].

Henkel, AW ;

Almers, W .

CURRENT OPINION IN NEUROBIOLOGY, 1996, 6 (03) :350-357

[9] STRUCTURE AND FUNCTION OF FUSION PORES IN EXOCYTOSIS AND ECTOPLASMIC MEMBRANE-FUSION [J].

LINDAU, M ;

ALMERS, W .

CURRENT OPINION IN CELL BIOLOGY, 1995, 7 (04) :509-517

[10] Kinetics of release of serotonin from isolated secretory granules .2. Ion exchange determines the diffusivity of serotonin [J].

Marszalek, PE ;

Farrell, B ;

Verdugo, P ;

Fernandez, JM .

BIOPHYSICAL JOURNAL, 1997, 73 (03) :1169-1183

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