Transcription factors, pancreatic development, and β-cell maintenance

被引:13
作者
Cerf, ME [1 ]
Muller, CJF
Du Toit, DF
Louw, J
Wolfe-Coote, SA
机构
[1] MRC, Diabet Res Grp, Tygerberg, South Africa
[2] Univ Stellenbosch, Dept Anat & Histol, ZA-7505 Tygerberg, South Africa
关键词
transcription factors; pancreas; development; diabetes;
D O I
10.1016/j.bbrc.2004.10.217
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transcription factors play an important role during pancreatic development ensuring normal differentiation of the islet endocrine cells. In mature P-cells, expression of specific transcription factors is essential in maintaining normal P-cell function, (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:699 / 702
页数:4
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