Electroneutral chloride-coupled co-transporters

被引：12

作者：

Gamba, G

机构：

[1] Inst Nacl Nutr Salvador Zubiran, Mol Physiol Unit, Mexico City 14000, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Invest Biomed, Mexico City 04510, DF, Mexico

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 2000年 / 9卷 / 05期

关键词：

D O I：

10.1097/00041552-200009000-00013

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The family of electroneutral chloride-coupled cc-transporters has been expanded in the past year by the identification of new genes or new alternatively spliced isoforms of already known genes. In this review, we discuss the molecular cloning of new members of the family, the knowledge revealed by the production of transgenic animals and some new aspects of the functional characteristics of cc-transporters. Curr Opin Nephrol Hypertens 9:535-540. (C) 2000 Lippincott Williams & Wilkins.

引用

页码：535 / 540

页数：6

共 45 条

[1] K-Cl cotransport in vascular smooth muscle and erythrocytes: possible implication in vasodilation [J].

Adragna, NC ;

White, RE ;

Orlov, SN ;

Lauf, PK .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2000, 278 (02) :C381-C390

[2] Vasoconstrictors and nitrovasodilators reciprocally regulate the Na+-K+-2Cl- cotransporter in rat aorta [J].

Akar, F ;

Skinner, E ;

Klein, JD ;

Jena, M ;

Paul, RJ ;

O'Neill, WC .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1999, 276 (06) :C1383-C1390

[3] CL--DEPENDENT NH4+ TRANSPORT MECHANISMS IN MEDULLARY THICK ASCENDING LIMB CELLS [J].

AMLAL, H ;

PAILLARD, M ;

BICHARA, M .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1994, 267 (06) :C1607-C1615

[4]

DELPIRE E, 1994, J BIOL CHEM, V269, P25677

[5] Deafness and imbalance associated with inactivation of the secretory Ma-K-2Cl co-transporter [J].

Delpire, E ;

Lu, JM ;

England, R ;

Dull, C ;

Thorne, T .

NATURE GENETICS, 1999, 22 (02) :192-195

[6] Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q [J].

Elmslie, FV ;

Rees, M ;

Williamson, MP ;

Kerr, M ;

Kjeldsen, MJ ;

Pang, KA ;

Sundqvist, A ;

Friis, ML ;

Chadwick, D ;

Richens, A ;

Covanis, A ;

Santos, M ;

Arzimanoglou, A ;

Panayiotopoulos, CP ;

Curtis, D ;

Whitehouse, WP ;

Gardiner, RM .

HUMAN MOLECULAR GENETICS, 1997, 6 (08) :1329-1334

[7] EFFECT OF OSMOLARITY ON CATION FLUXES IN MEDULLARY THICK ASCENDING LIMB CELLS [J].

EVELOFF, JL ;

CALAMIA, J .

AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 250 (01) :F176-F180

[8] Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf [J].

Flagella, M ;

Clarke, LL ;

Miller, ML ;

Erway, LC ;

Giannella, RA ;

Andringa, A ;

Gawenis, LR ;

Kramer, J ;

Duffy, JJ ;

Doetschman, T ;

Lorenz, JN ;

Yamoah, EN ;

Cardell, EL ;

Shull, GE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (38) :26946-26955

[9] PRIMARY STRUCTURE AND FUNCTIONAL EXPRESSION OF A CDNA-ENCODING THE THIAZIDE-SENSITIVE, ELECTRONEUTRAL SODIUM-CHLORIDE COTRANSPORTER [J].

GAMBA, G ;

SALTZBERG, SN ;

LOMBARDI, M ;

MIYANOSHITA, A ;

LYTTON, J ;

HEDIGER, MA ;

BRENNER, BM ;

HEBERT, SC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (07) :2749-2753

[10]

GAMBA G, 1994, J BIOL CHEM, V269, P17713

← 1 2 3 4 5 →