Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn. (Palmae) husk fiber extract

被引：189

作者：

Esquenazi, D ^{[1
]}

Wigg, MD

Miranda, MMFS

Rodrigues, HM

Tostes, JBF

Rozental, S

da Silva, AJR

Alviano, CS

机构：

[1] Univ Fed Rio de Janeiro, Inst Biofis Carlos Chagas Filho, Lab Biol Celular Fungos, BR-21941590 Rio De Janeiro, Brazil

[2] Univ Fed Rio de Janeiro, Inst Microbiol Professor Paulo De Goes, Lab Expt Drogas Antivirais & Citotoxicas, BR-21941590 Rio De Janeiro, Brazil

[3] Univ Fed Rio de Janeiro, Inst Microbiol Professor Paulo De Goes, Lab Estruturas Superficie Microorganismos, BR-21941590 Rio De Janeiro, Brazil

来源：

RESEARCH IN MICROBIOLOGY | 2002年 / 153卷 / 10期

关键词：

Cocos nucifera; antimicrobial activity; antiviral activity; catechins; condensed tannins;

D O I：

10.1016/S0923-2508(02)01377-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The decoction of Cocos nucifera L. husk fiber has been used in northeastern Brazil traditional medicine for treatment of diarrhea and arthritis. Water extract obtained from coconut husk fiber and fractions from adsorption chromatography revealed antimicrobial activity against Staphylococcus aureus. The crude extract and one of the fractions rich in catechin also showed inhibitory activity against acyclovir-resistant herpes simplex virus type 1 (HSV-1-ACVr). All fractions were inactive against the fungi Candida albicans, Fonsecaea pedrosoi and Cryptococcus neoformans. Catechin and epicatechin together with condensed tannins (B-type procyanidins) were demonstrated to be the components of the water extract. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：647 / 652

页数：6

共 33 条

[1]

BODEY GP, 1984, AM J MED, V77, pU1

[2] A novel approach for the quantitative kinetic study of reactions at solid/liquid interfaces in the presence of power ultrasound [J].

Booth, J ;

Compton, RG ;

Hill, E ;

Marken, F ;

Rebbitt, TO .

ULTRASONICS SONOCHEMISTRY, 1997, 4 (01) :1-7

[3] EFFICACY OF S26308 AGAINST GUINEA-PIG CYTOMEGALO-VIRUS INFECTION [J].

CHEN, M ;

GRIFFITH, BP ;

LUCIA, HL ;

HSIUNG, GD .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (05) :678-683

[4]

Chosa H, 1992, Kansenshogaku Zasshi, V66, P606

[5] Plant products as antimicrobial agents [J].

Cowan, MM .

CLINICAL MICROBIOLOGY REVIEWS, 1999, 12 (04) :564-+

[6] Biological evaluation of proanthocyanidin dimers and related polyphenols [J].

De Bruyne, T ;

Pieters, L ;

Witvrouw, M ;

De Clercq, E ;

Vanden Berghe, D ;

Vlietinck, AJ .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (07) :954-958

[7] PHARMACOGNOSY - THE OLDEST MODERN SCIENCE [J].

DEPASQUALE, A .

JOURNAL OF ETHNOPHARMACOLOGY, 1984, 11 (01) :1-16

[8]

Dromer F, 1996, J MYCOL MED, V6, P1

[9]

Duke JA, 1992, HDB PHYTOCHEMICAL CO

[10] PROCYANIDIN POLYMERS OF DOUGLAS-FIR BARK - STRUCTURE FROM DEGRADATION WITH PHLOROGLUCINOL [J].

FOO, LY ;

KARCHESY, JJ .

PHYTOCHEMISTRY, 1989, 28 (11) :3185-3190

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