Carrying out an optimal experiment

被引：21

作者：

Dauter, Zbigniew ^{[1
]}

机构：

[1] NCI, Synchrotron Radiat Res Sect, MCL, Argonne Natl Lab, Argonne, IL 60439 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2010年 / 66卷

关键词：

DIFFRACTION DATA-COLLECTION; RADIATION; STRATEGIES; REFINEMENT; SAD;

D O I：

10.1107/S0907444909038578

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Diffraction data collection is the last experimental stage in structural crystallography. It has several technical and theoretical aspects and a compromise usually has to be found between various parameters in order to achieve optimal data quality. The influence and importance of various experimental parameters and their consequences are discussed in the context of different data applications, such as molecular replacement, anomalous phasing, high-resolution refinement or searching for ligands.

引用

页码：389 / 392

页数：4

共 18 条

[1]

Arndt U.W., 1977, The Rotation Method in Crystallography: Data Collection from Macromolecular Crystals

[2] A quantitative approach to data-collection strategies [J].

Bourenkov, GP ;

Popov, AN .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2006, 62 :58-64

[3] Efficient use of synchrotron radiation for macromolecular diffraction data collection [J].

Dauter, Z .

PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2005, 89 (02) :153-172

[4] Data-collection strategies [J].

Dauter, Z .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 1999, 55 :1703-1717

[5]

DAVIES GJ, 1993, P CCP4 STUD WEEK DAT, P132

[6] Is it jolly SAD? [J].

Dodson, E .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2003, 59 :1958-1965

[7] The befores and afters of molecular replacement [J].

Dodson, Eleanor .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2008, 64 :17-24

[8] Whither structural biology? [J].

Harrison, SC .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (01) :12-15

[9] Phase determination from multiwavelength anomalous diffraction measurements [J].

Hendrickson, WA ;

Ogata, CM .

MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 :494-523

[10]

Kleywegt GJ, 2007, ACTA CRYSTALLOGR D, V63, P94, DOI [10.1107/S0907444906022657, 10.1107/S907444906022657]

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