Adherence to antiretroviral therapy: are we doing enough?

被引：17

作者：

Read, T

Mijch, A

Fairley, CK

机构：

[1] Melbourne Sexual Hlth Ctr, Carlton, Vic 3053, Australia

[2] Alfred Hosp, HIV Serv, Melbourne, Vic, Australia

[3] Univ Melbourne, Dept Publ Hlth, Melbourne, Vic, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2003年 / 33卷 / 5-6期

关键词：

adherence; antiretroviral therapy; compliance;

D O I：

10.1046/j.1445-5994.2003.00333.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adherence to antiretroviral therapy is a powerful predictor of response to therapy. For optimal antiretroviral therapy response, individuals need to take more than 95% of their prescribed medication. The most widely used method for measuring adherence is self-report of the number of missed doses and this should be done at every clinic visit. There are several well-recognized predictors of poor adherence, such as illicit drug use, depression, limited knowledge or ambivalence about starting treatment. Adherence can be improved by addressing these issues or through other means such as pill boxes or electronic reminders.

引用

收藏

页码：254 / 256

页数：3

相关论文

共 18 条

[1] Measured versus self-reported compliance with doxycycline therapy for chlamydia-associated syndromes - High therapeutic success rates despite poor compliance [J].

Bachmann, LH ;

Stephens, J ;

Richey, CM ;

Hook, EW .

SEXUALLY TRANSMITTED DISEASES, 1999, 26 (05) :272-278

[2] Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population [J].

Bangsberg, DR ;

Hecht, FM ;

Charlebois, ED ;

Zolopa, AR ;

Holodniy, M ;

Sheiner, L ;

Bamberger, JD ;

Chesney, MA ;

Moss, A .

AIDS, 2000, 14 (04) :357-366

[3] Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults [J].

Bartlett, JA ;

DeMasi, R ;

Quinn, J ;

Moxham, C ;

Rousseau, F .

AIDS, 2001, 15 (11) :1369-1377

[4]

BURGESS JD, 2001, AUSTR SOC HIV MED C

[5] Psychosocial factors are associated with prolonged hospitalization in a population with advanced HIV [J].

Cheng, AC ;

Mijch, AM ;

Hoy, JF ;

Wesselingh, SL ;

Fairley, CK .

INTERNATIONAL JOURNAL OF STD & AIDS, 2001, 12 (05) :302-306

[6] HIV disease progression in Australia in the time of combination antiretroviral therapies [J].

Correll, PK ;

Law, MG ;

McDonald, AM ;

Cooper, DA ;

Kaldor, JM .

MEDICAL JOURNAL OF AUSTRALIA, 1998, 169 (09) :469-472

[7] HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: Response to both initial and salvage therapy [J].

Deeks, SG ;

Hecht, FM ;

Swanson, M ;

Elbeik, T ;

Loftus, R ;

Cohen, PT ;

Grant, RM .

AIDS, 1999, 13 (06) :F35-F43

[8]

FAUCI AS, 2002, GUIDELINES USE ANTIR

[9] The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response [J].

Haubrich, RH ;

Little, SJ ;

Currier, JS ;

Forthal, DN ;

Kemper, CA ;

Beall, GN ;

Johnson, D ;

Dubé, MP ;

Hwang, JY ;

McCutchan, JA .

AIDS, 1999, 13 (09) :1099-1107

[10]

HENRY J, 1998, MMWR, V47