Dopamine D4 receptor gene polymorphism and personality traits in healthy volunteers

被引：25

作者：

Persson, ML ^{[1
]}

Wasserman, D

Geijer, T

Frisch, A

Rockah, R

Michaelovsky, E

Apter, A

Weizman, A

Jönsson, EG

Bergman, H

机构：

[1] Natl Inst Psychosocial Factors & Hlth, Natl & Stockholm Cty Counc Ctr Suicide Res & Prev, SE-17177 Stockholm, Sweden

[2] Karolinska Inst, Dept Publ Hlth Sci, SE-17177 Stockholm, Sweden

[3] Karolinska Inst, Psychol Sect, Dept Clin Neurosci Occupat Therapy & Elderly Care, SE-14186 Stockholm, Sweden

[4] Tel Aviv Univ, Rabin Med Ctr, Felsenstein Med Res Ctr, IL-69978 Tel Aviv, Israel

[5] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

[6] Geha Psychiat Hosp, Rabin Med Ctr, Petah Tiqwa, Israel

[7] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel

[8] Karolinska Inst, Psychiat Sect, Dept Clin Neurosci, Stockholm, Sweden

[9] Karolinska Inst, Dept Clin Neurosci, Clin Alcohol & Drug Addict Res Sect, Stockholm, Sweden

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 2000年 / 250卷 / 04期

关键词：

dopamine receptor D4; genetics; personality inventory; polymorphism; Excitement-Seeking;

D O I：

10.1007/s004060070025

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

An association between long alleles of a variable number tandem repeat (VNTR) polymorphism in the dopamine receptor D4 gene and the extraversion related personality traits Excitement and Novelty Seeking has been reported in healthy subjects. In an attempt to replicate the previous findings, 256 healthy Caucasian volunteers were analysed for a potential relationship between the dopamine receptor D4 exon III VNTR polymorphism and Extraversion as assessed by the Revised Neo Personality Inventory (NEO PI-R). The present study did not yield evidence for an association between Extraversion and the dopamine receptor D4 polymorphism.

引用

页码：203 / 206

页数：4

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