Chimeric 16S rDNA sequences of diverse origin are accumulating in the public databases

被引：172

作者：

Hugenholtz, P ^{[1
]}

Huber, T ^{[1
]}

机构：

[1] Univ Queensland, ComBinE Grp, Adv Computat Modelling Ctr, Brisbane, Qld 4072, Australia

来源：

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY | 2003年 / 53卷

关键词：

D O I：

10.1099/ijs.0.02441-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A significant number of chimeric 16S rDNA sequences of diverse origin were identified in the public databases by partial treeing analysis. This suggests that chimeric sequences, representing phylogenetically novel non-existent organisms, are routinely being overlooked in molecular phylogenetic surveys despite a general awareness of PCR-generated artefacts amongst researchers.

引用

页码：289 / 293

页数：5

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