Specificity in signaling by c-Yes

被引：23

作者：

Summy, JM

Sudol, M

Eck, MJ

Monteiro, AN

Gatesman, A

Flynn, DC

机构：

[1] W Virginia Univ, Mary Babb Randolph Canc Ctr, Sch Med, Morgantown, WV 26506 USA

[2] W Virginia Univ, Dept Microbiol & Immunol, Morgantown, WV 26506 USA

[3] Mt Sinai Sch Med, Dept Biochem, New York, NY USA

[4] Beth Israel Deaconess Med Ctr, Div Hematol Oncol, Boston, MA 02215 USA

[5] Cornell Univ, Strang Canc Prevent Ctr, New York, NY USA

[6] Cornell Univ, Weil Med Coll, New York, NY USA

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2003年 / 8卷

关键词：

Src; Yes; tyrosine kinases; review;

D O I：

10.2741/1011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

c-Yes and c-Src are the two most closely related members of the Src family of nonreceptor tyrosine kinases. Although there is much evidence to support redundancy in signaling between these two kinases, there is also a growing body of evidence to indicate specificity in signaling. In this review, we summarize c-Yes, its potential functions and its ability to modulate signals that are distinct from c-Src.

引用

页码：S185 / S205

页数：21

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