Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2)

被引：40

作者：

Poralla, K ^{[1
]}

Muth, G ^{[1
]}

Härtner, T ^{[1
]}

机构：

[1] Univ Tubingen, Inst Microbiol, D-72076 Tubingen, Germany

来源：

FEMS MICROBIOLOGY LETTERS | 2000年 / 189卷 / 01期

关键词：

isoprenoid; hopanoid; differentiation; Streptomyces coelicolor;

D O I：

10.1016/S0378-1097(00)00259-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Streptomyces coelicolor A3(2) contains a cluster of putative isoprenoid and hopanoid biosynthetic genes. The strain does not produce the pentacyclic hopanoids in liquid culture but produces them on solid medium when sporulating. Mutants defective in the formation of aerial mycelium and spores (bld), with the exception of bldB, do not synthesize hopanoids, whereas mutants, which form aerial mycelium but no spores (whi), do. The membrane condensing hopanoids possibly may alleviate stress in aerial mycelium by diminishing water permeability across the membrane. (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：93 / 95

页数：3

共 15 条

[1] A DIRECT STUDY OF THE COHESION OF LECITHIN BILAYERS - THE EFFECT OF HOPANOIDS AND ALPHA,OMEGA-DIHYDROXYCAROTENOIDS [J].

BISSERET, P ;

WOLFF, G ;

ALBRECHT, AM ;

TANAKA, T ;

NAKATANI, Y ;

OURISSON, G .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 110 (01) :320-324

[2]

BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911

[3] Taking a genetic scalpel to the Streptomyces colony [J].

Chater, KF .

MICROBIOLOGY-UK, 1998, 144 :1465-1478

[4] Molecular basis of symbiosis between Rhizobium and legumes [J].

Freiberg, C ;

Fellay, R ;

Bairoch, A ;

Broughton, WJ ;

Rosenthal, A ;

Perret, X .

NATURE, 1997, 387 (6631) :394-401

[5] MUTANTS BLOCKED IN STREPTOMYCIN PRODUCTION IN STREPTOMYCES-GRISEUS - THE ROLE OF A-FACTOR [J].

HARA, O ;

BEPPU, T .

JOURNAL OF ANTIBIOTICS, 1982, 35 (03) :349-358

[6] Hopanoid biosynthesis and function in bacteria [J].

Kannenberg, EL ;

Poralla, K .

NATURWISSENSCHAFTEN, 1999, 86 (04) :168-176

[7]

KANNENBERG EL, 1996, PLANT SOIL, V186, P105

[8] IMPORTANCE OF STORED TRIACYLGLYCEROLS IN STREPTOMYCES - POSSIBLE CARBON SOURCE FAR ANTIBIOTICS [J].

OLUKOSHI, ER ;

PACKTER, NM .

MICROBIOLOGY-SGM, 1994, 140 :931-943

[9] Cloning of conserved genes from Zymomonas mobilis and Bradyrhizobium japonicum that function in the biosynthesis of hopanoid lipids [J].

Perzl, M ;

Reipen, IG ;

Schmitz, S ;

Poralla, K ;

Sahm, H ;

Sprenger, GA ;

Kannenberg, EL .

BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, 1998, 1393 (01) :108-118

[10] The bldB gene encodes a small protein required for morphogenesis, antibiotic production, and catabolite control in Streptomyces coelicolor [J].

Pope, MK ;

Green, B ;

Westpheling, J .

JOURNAL OF BACTERIOLOGY, 1998, 180 (06) :1556-1562

← 1 2 →