In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe

被引：8

作者：

Ansari, RR ^{[1
]}

Suh, KI ^{[1
]}

Tumminia, SJ ^{[1
]}

Russell, P ^{[1
]}

Zigler, JS ^{[1
]}

机构：

[1] NASA, Lewis Res Ctr, CWRU, Cleveland, OH 44135 USA

来源：

MEDICAL APPLICATIONS OF LASERS IN DERMATOLOGY, OPHTHALMOLOGY, DENTISTRY, AND ENDOSCOPY, PROCEEDINGS OF | 1997年 / 3192卷

关键词：

D O I：

10.1117/12.297843

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

A compact fiber optic probe developed by Ansari et al.(1) for fluids experiments in the challenging conditions of a microgravity environment on-board a space shuttle orbiter has been applied to obtain "cataractograms" in transgenic mice to study early onset of cataractogenesis. Cataractograms are topographical contour maps of the lens which are obtained noninvasively by scanning the eye with the probe in three-dimensions (x, y, and z directions). This new method provides a visual means, in false color, for quantitative detection and monitoring of cataracts in the entire lens. The portion of lens mapped is only Limited by the degree of pupil dilation. The dilated pupil is about 1 mm for the transgenic mice system reported in this study.

引用

页码：202 / 210

页数：9