La mala educacion of Tumor-Associated Macrophages: Diverse Pathways and New Players

被引：21

作者：

Mantovani, Alberto ^{[1
,2
]}

机构：

[1] IRCCS, Ist Clin Humanitas, I-20089 Rozzano, Italy

[2] Univ Milan, Dept Translat Med, I-20122 Milan, Italy

来源：

CANCER CELL | 2010年 / 17卷 / 02期

关键词：

IMMUNE SURVEILLANCE; PROGRESSION; METASTASIS; PHENOTYPE; PROTUMOR;

D O I：

10.1016/j.ccr.2010.01.019

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Inflammation is a key component of the tumor microenvironment. Two reports published in this issue of Cancer Cell, Andreu et al. and Erez et al., shed new light on pathways and players involved in the orchestration of cancer-related inflammation.

引用

页码：111 / 112

页数：2

共 11 条

[1] The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance [J].

Allavena, Paola ;

Sica, Antonio ;

Garlanda, Cecilia ;

Mantovani, Alberto .

IMMUNOLOGICAL REVIEWS, 2008, 222 :155-161

[2] FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis [J].

Andreu, Pauline ;

Johansson, Magnus ;

Affara, Nesrine I. ;

Pucci, Ferdinando ;

Tan, Tingting ;

Junankar, Simon ;

Korets, Lidiya ;

Lam, Julia ;

Tawfik, David ;

DeNardo, David G. ;

Naldini, Luigi ;

de Visser, Karin E. ;

De Palma, Michele ;

Coussens, Lisa M. .

CANCER CELL, 2010, 17 (02) :121-134

[3] CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages [J].

DeNardo, David G. ;

Barreto, Jairo B. ;

Andreu, Pauline ;

Vasquez, Lesley ;

Tawfik, David ;

Kolhatkar, Nikita ;

Coussens, Lisa M. .

CANCER CELL, 2009, 16 (02) :91-102

[4] Immunological and Inflammatory Functions of the Interleukin-1 Family [J].

Dinarello, Charles A. .

ANNUAL REVIEW OF IMMUNOLOGY, 2009, 27 :519-550

[5] Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner [J].

Erez, Neta ;

Truitt, Morgan ;

Olson, Peter ;

Hanahan, Douglas .

CANCER CELL, 2010, 17 (02) :135-147

[6] Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: "N1" versus "N2" TAN [J].

Fridlender, Zvi G. ;

Sun, Jing ;

Kim, Samuel ;

Kapoor, Veena ;

Cheng, Guanjun ;

Ling, Leona ;

Worthen, G. Scott ;

Albelda, Steven M. .

CANCER CELL, 2009, 16 (03) :183-194

[7] Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype [J].

Hagemann, Thorsten ;

Wilson, Julia ;

Burke, Frances ;

Kulbe, Hagen ;

Li, Ninfeng Fiona ;

Pluddemann, Annette ;

Charles, Kellie ;

Gordon, Siamon ;

Balkwill, Frances R. .

JOURNAL OF IMMUNOLOGY, 2006, 176 (08) :5023-5032

[8] Cancer-related inflammation [J].

Mantovani, Alberto ;

Allavena, Paola ;

Sica, Antonio ;

Balkwill, Frances .

NATURE, 2008, 454 (7203) :436-444

[9] Modulation of the antitumor immune response by complement [J].

Markiewski, Maciej M. ;

DeAngelis, Robert A. ;

Benencia, Fabian ;

Ricklin-Lichtsteiner, Salome K. ;

Koutoulaki, Anna ;

Gerard, Craig ;

Coukos, George ;

Lambris, John D. .

NATURE IMMUNOLOGY, 2008, 9 (11) :1225-1235

[10] Immune surveillance: a balance between protumor and antitumor immunity [J].

Ostrand-Rosenberg, Suzanne .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2008, 18 (01) :11-18

← 1 2 →