Synaptic ribbon: Conveyor belt or safety belt?

被引：119

作者：

Parsons, TD ^{[1
]}

Sterling, P

机构：

[1] Univ Penn, Sch Vet Med, Dept Clin Studies, New Bolton Ctr, Philadelphia, PA 19104 USA

[2] Univ Penn, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Philadelphia, PA 19104 USA

[3] Univ Penn, Sch Med, Dept Neurosci, Philadelphia, PA 19104 USA

来源：

NEURON | 2003年 / 37卷 / 03期

关键词：

D O I：

10.1016/S0896-6273(03)00062-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The synaptic ribbon in neurons that release transmitter via graded potentials has been considered as a conveyor belt that actively moves vesicles toward their release sites. But evidence has accumulated to the contrary, and it now seems plausible that the ribbon serves instead as a safety belt to tether vesicles stably in mutual contact and thus facilitate multivesicular release by compound exocytosis.

引用

页码：379 / 382

页数：4

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