Supramolecular synthon polymorphism in 2 : 1 co-crystal of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine

被引：127

作者：

Sreekanth, B. R. ^{[1
]}

Vishweshwar, Peddy ^{[1
]}

Vyas, K. ^{[1
]}

机构：

[1] Dr Reddys Labs Ltd, Dept Analyt Res, Discovery Res, Hyderabad 500049, Andhra Pradesh, India

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 23期

关键词：

PHARMACEUTICAL PHASES; HYDROGEN-BONDS; SOLID-STATE; TRICLINIC POLYMORPHS; MOLECULAR-COMPLEXES; COCRYSTALS; DESIGN; CONCOMITANT; 1/1-COMPLEX; TAPES;

D O I：

10.1039/b700082k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Co-crystals of 4-hydroxybenzoic acid and 2,3,5,6-tetramethylpyrazine (2 : 1) exhibit the first supramolecular synthon polymorphism in a co-crystal; metastable anti-hierarchic polymorph I converts to stable hierarchic form II.

引用

页码：2375 / 2377

页数：3

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