Yeast gene YOR137c is involved in the activation of the yeast plasma membrane H+-ATPase by glucose

被引：14

作者：

de la Fuente, N

Maldonado, AM

Portillo, F

机构：

[1] Univ Autonoma Madrid, Fac Med, Dept Bioquim, E-28029 Madrid, Spain

[2] CSIC, Inst Invest Biomed, E-28029 Madrid, Spain

来源：

FEBS LETTERS | 1997年 / 420卷 / 01期

关键词：

H+-ATPase; plasma membrane; glucose activation; Saccharomyces cerevisiae;

D O I：

10.1016/S0014-5793(97)01478-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Glucose triggers transcriptional and post-transcriptional mechanisms that increase the level and activity of Saccharomyces cerevisiae plasma membrane H+-ATPase, We have studied the post-transcriptional activation of the enzyme by glucose and have found that the YOR137c gene product is implicated in this activation. Deletion of YOR137c does not affect the level of Pma1 at the plasma membrane, but disturbs the glucose-triggered V-max increase of the enzyme, We propose that at least two independent mechanisms are involved in glucose activation of the H+-ATPase, (C) 1997 Federation of European Biochemical Societies.

引用

页码：17 / 19

页数：3

共 31 条

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