Cadaver donor screening for infectious agents in solid organ transplantation

被引:42
作者
Delmonico, FL [1 ]
机构
[1] New England Organ Bank, Gateway Ctr 1, Newton, MA USA
[2] Harvard Univ, Sch Med, Newton, MA USA
关键词
D O I
10.1086/314000
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The transmission of infection by a cadaver donor organ can result not only in loss of the allograft but also in death of the immunosuppressed recipient. Despite the shortage of cadaver organ donors, every donor must be evaluated thoroughly for the potential transmission of infectious disease, because the consequences of the organ donor events can have a profound effect on the transplant outcome. This review summarizes current knowledge about serological screening of organ donors to determine the suitability of organs from cadaver donors for transplantation.
引用
收藏
页码:781 / 786
页数:6
相关论文
共 28 条
[1]   Hepatitis C after orthotopic liver transplantation [J].
Araya, V ;
Rakela, J ;
Wright, T .
GASTROENTEROLOGY, 1997, 112 (02) :575-582
[2]  
*CDC, 1987, JAMA-J AM MED ASSOC, V258, P309
[3]   THE IMPACT OF DONOR AND RECIPIENT HEPATITIS-B SURFACE-ANTIGEN STATUS ON LIVER-DISEASE AND SURVIVAL IN RENAL-TRANSPLANT RECIPIENTS [J].
CHAN, PCK ;
LOK, ASF ;
CHENG, IKP ;
CHAN, MK .
TRANSPLANTATION, 1992, 53 (01) :128-131
[4]   Severe clinical course of de novo hepatitis B infection after liver transplantation [J].
Crespo, J ;
Fábrega, E ;
Casafont, F ;
Rivero, M ;
de las Heras, G ;
de la Peña, J ;
de la Cruz, F ;
Pons-Romero, F .
LIVER TRANSPLANTATION AND SURGERY, 1999, 5 (03) :175-183
[5]   Organ donor screening for infectious diseases - Review of practice and implications for transplantation [J].
Delmonico, FL ;
Snydman, DR .
TRANSPLANTATION, 1998, 65 (05) :603-610
[6]   Transmission of hepatitis B by transplantation of livers from donors positive for antibody to hepatitis B core antigen [J].
Dickson, RC ;
Everhart, JE ;
Lake, JR ;
Wei, YL ;
Seaberg, EC ;
Wiesner, RH ;
Zetterman, RK ;
Pruett, TL ;
Ishitani, MB ;
Hoofnagle, JH ;
Detre, KM ;
Demetris, AJ ;
Lombardero, M ;
Seaberg, E ;
Lawlor, S ;
Fitzgerald, S ;
Haber, J ;
Swanson, GL ;
Wiesner, R ;
Krom, R ;
Porayko, MK ;
Schwerman, L ;
Groettum, C ;
Shaw, B ;
Taylor, K ;
Ascher, N ;
Lake, J ;
BremerKamp, C ;
Everhart, J ;
Shores, S ;
Broccoli, A ;
Hausman, G ;
Shepard, B ;
Carrol, N ;
McGory, R ;
Stevenson, WC ;
McCullough, C ;
Caldwell, S .
GASTROENTEROLOGY, 1997, 113 (05) :1668-1674
[7]   THE RISK OF TRANSFUSION-TRANSMITTED INFECTION [J].
DODD, RY .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (06) :419-421
[8]   Prevention of de novo hepatitis B infection in recipients of hepatic allografts from anti-HBc positive donors [J].
Dodson, SF ;
Bonham, CA ;
Geller, DA ;
Cacciarelli, TV ;
Rakela, J ;
Fung, JJ .
TRANSPLANTATION, 1999, 68 (07) :1058-1061
[9]   LACK OF PROTECTIVE IMMUNITY AGAINST REINFECTION WITH HEPATITIS-C VIRUS [J].
FARCI, P ;
ALTER, HJ ;
GOVINDARAJAN, S ;
WONG, DC ;
ENGLE, R ;
LESNIEWSKI, RR ;
MUSHAHWAR, IK ;
DESAI, SM ;
MILLER, RH ;
OGATA, N ;
PURCELL, RH .
SCIENCE, 1992, 258 (5079) :135-140
[10]  
FIRLIT CF, 1974, ARCH SURG-CHICAGO, V109, P797