The synthesis of 1-aminodihydroisoquinolines by an imine addition-cyclisation reaction.

被引：10

作者：

Beaton, H ^{[1
]}

Hamley, P ^{[1
]}

Tinker, AC ^{[1
]}

机构：

[1] Astra Charnwood, Dept Med Chem, Loughborough LE11 5RH, Leics, England

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(97)10736-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of 1-amino-3,4-dihydroisoquinolines substituted at the 3-position and related thienopyridines were prepared by lithiation of ortho-methyl aromatic nitriles, addition to N-trimethylsilylimines and spontaneous cyclisation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1227 / 1230

页数：4

共 19 条

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