Fraternal twins: AQP1 and GlpF

被引:19
作者
Unger, VM [1 ]
机构
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
关键词
D O I
10.1038/81914
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The electron and X-ray crystallographic structures of AQP1 and GlpF, respectively, provide insights into the mechanisms of how water and small solutes such as glycerol selectively traverse lipid bilayers.
引用
收藏
页码:1082 / 1084
页数:3
相关论文
共 23 条
[1]   An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors [J].
Baldwin, JM ;
Schertler, GFX ;
Unger, VM .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 272 (01) :144-164
[2]   THE PROBABLE ARRANGEMENT OF THE HELICES IN G-PROTEIN-COUPLED RECEPTORS [J].
BALDWIN, JM .
EMBO JOURNAL, 1993, 12 (04) :1693-1703
[3]   Structure of the MscL homolog from Mycobacterium tuberculosis:: A gated mechanosensitive ion channel [J].
Chang, G ;
Spencer, RH ;
Lee, AT ;
Barclay, MT ;
Rees, DC .
SCIENCE, 1998, 282 (5397) :2220-2226
[4]   Three-dimensional organization of a human water channel [J].
Cheng, AC ;
vanHoek, AN ;
Yeager, M ;
Verkman, AS ;
Mitra, AK .
NATURE, 1997, 387 (6633) :627-630
[5]   Effect of PCMBS on CO2 permeability of Xenopus oocytes expressing aquaporin 1 or its C189S mutant [J].
Cooper, GJ ;
Boron, WF .
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1998, 275 (06) :C1481-C1486
[6]   The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].
Doyle, DA ;
Cabral, JM ;
Pfuetzner, RA ;
Kuo, AL ;
Gulbis, JM ;
Cohen, SL ;
Chait, BT ;
MacKinnon, R .
SCIENCE, 1998, 280 (5360) :69-77
[7]   The importance of aquaporin water channel protein structures [J].
Engel, A ;
Fijiyoshi, Y ;
Agre, P .
EMBO JOURNAL, 2000, 19 (05) :800-806
[8]   Structure of a glycerol-conducting channel and the basis for its selectivity [J].
Fu, DX ;
Libson, A ;
Miercke, LJW ;
Weitzman, C ;
Nollert, P ;
Krucinski, J ;
Stroud, RM .
SCIENCE, 2000, 290 (5491) :481-486
[9]   Structural clues in the sequences of the aquaporins [J].
Heymann, JB ;
Engel, A .
JOURNAL OF MOLECULAR BIOLOGY, 2000, 295 (04) :1039-1053
[10]   STRUCTURE OF THE OSMO-REGULATED H2O-CHANNEL, AQP-CHIP, IN PROJECTION AT 3.5 ANGSTROM RESOLUTION [J].
JAP, BK ;
LI, HL .
JOURNAL OF MOLECULAR BIOLOGY, 1995, 251 (03) :413-420