Application of ene-like reactions of aldehydes with vinyl ethers: Facile assembly of benzazocenone intermediates for mitomycinoids

被引：14

作者：

Ciufolini, MA

Chen, MY

Lovett, DP

Deaton, MV

机构：

[1] Department of Chemistry, MS 60, Rice University, Houston, TX 77005-1892

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(97)00933-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzazocenone intermediates for mitomycinoids are now available in only six steps. Key phases of this sequence include the ene-like reaction of 2-methoxypropene with a 2-azidophenyacetaldehyde and a novel heterocyclic ring formation/expansion reaction. (C) 1997 Elsevier Science Ltd.

引用

页码：4355 / 4358

页数：4

共 16 条

[1]

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[2]

CIUFOLINI MA, 1996, ADV HETEROCYCLIC NAT, V3, pCH1

[3]

CIUFOLINI MA, 1997, IN PRESS TETRAHEDRON, V53

[4] A STEREOSPECIFIC ROUTE TO AZIRIDINOMITOSANES - THE SYNTHESIS OF NOVEL MITOMYCIN CONGENERS [J].