Novel metabolism in Chlamydomonas through the lens of genomics

被引:114
作者
Grossman, Arthur R.
Croft, Martin
Gladyshev, Vadim N.
Merchant, Sabeeha S.
Posewitz, Matthew C.
Prochnik, Simon
Spalding, Martin H.
机构
[1] Carnegie Inst Sci, Dept Plant Biol, Stanford, CA 94305 USA
[2] Univ Cambridge, Dept Plant Sci, Cambridge CB2 1TN, England
[3] Univ Nebraska, Dept Biochem, Lincoln, NE 68588 USA
[4] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA
[5] Colorado Sch Mines, Environm Sci & Engn Div, Golden, CO 80401 USA
[6] DOE Joint Genome Inst, Walnut Creek, CA USA
[7] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
D O I
10.1016/j.pbi.2007.01.012
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Chlamydomonas has traditionally been exploited as an organism that is associated with sophisticated physiological, genetic and molecular analyses, all of which have been used to elucidate several biological processes, especially photosynthesis and flagella function and assembly. Recently, the genomics of Chlamydomonas has been combined with other technologies to unveil new aspects of metabolism, including inorganic carbon utilization, anaerobic fermentation, the suite and functions of selenoproteins, and the regulation of vitamin biosynthesis. These initial findings represent the first glimpse through a genomic window onto the highly complex metabolisms that characterize a unicellular, photosynthetic eukaryote that has maintained both plant-like and animal-like characteristics over evolutionary time.
引用
收藏
页码:190 / 198
页数:9
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