Continuous non-seasonal epidemic of respiratory syncytial virus infection in the southeast United States

被引:34
作者
Halstead, DC
Jenkins, SG
机构
[1] Baptist St Vincents Hlth Syst, Dept Pathol, Jacksonville, AL USA
[2] Univ Med Ctr, Dept Pathol, Jacksonville, AL USA
关键词
D O I
10.1097/00007611-199805000-00004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. This study was done to define the seasonality of respiratory syncytial virus (RSV) epidemics in the southeastern United States. Methods. We tested 5,092 fresh nasal aspirates or washings, using the Kallestad Pathfinder enzyme immunoassay (EIA) or the Directigen RSV membrane EIA according to manufacturers' directions. Results. A total of 1,419 (27.9%) respiratory specimens, collected from pediatric patients between May 1993 and December 1996 at two large southeastern medical centers, were positive for RSV antigen by enzyme immunoassay. A persistent RSV epidemic was documented between July 1993 and December 1996. We defined an epidemic as 2 consecutive months in each of which greater than or equal to 10% of the specimens were positive and greater than or equal to 2 positive specimens detected. The highest percentages of positive specimens were detected in December of 1993, 1994, and 1996, to date, and November 1995. Conclusion, On the basis of our findings, we recommend health care workers consider RSV in the differential diagnosis of acute respiratory illness throughout the year in pediatric patients from the southeast United States.
引用
收藏
页码:433 / 436
页数:4
相关论文
共 14 条
  • [1] ASSOCIATION BETWEEN RESPIRATORY SYNCYTIAL VIRUS OUTBREAKS AND LOWER RESPIRATORY-TRACT DEATHS OF INFANTS AND YOUNG-CHILDREN
    ANDERSON, LJ
    PARKER, RA
    STRIKAS, RL
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1990, 161 (04) : 640 - 646
  • [2] *CDCP, 1996, MMWR-MORBID MORTAL W, V45, P1053
  • [3] NATIONAL SURVEILLANCE FOR RESPIRATORY SYNCYTIAL VIRUS, UNITED-STATES, 1985-1990
    GILCHRIST, S
    TOROK, TJ
    GARY, HE
    ALEXANDER, JP
    ANDERSON, LJ
    [J]. JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (04) : 986 - 990
  • [4] PROPHYLACTIC ADMINISTRATION OF RESPIRATORY SYNCYTIAL VIRUS IMMUNE GLOBULIN TO HIGH-RISK INFANTS AND YOUNG-CHILDREN
    GROOTHUIS, JR
    SIMOES, EAF
    LEVIN, MJ
    HALL, CB
    LONG, CE
    RODRIGUEZ, WJ
    ARROBIO, J
    MEISSNER, HC
    FULTON, DR
    WELLIVER, RC
    TRISTRAM, DA
    SIBER, GR
    PRINCE, GA
    VANRADEN, M
    HEMMING, VG
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (21) : 1524 - 1530
  • [5] GROOTHUIS JR, 1995, PEDIATRICS, V95, P463
  • [6] Hall C.B., 1992, TXB PEDIAT INFECT DI, P1633
  • [7] EVALUATION OF 5 METHODS FOR RESPIRATORY SYNCYTIAL VIRUS DETECTION
    HALSTEAD, DC
    TODD, S
    FRITCH, G
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1990, 28 (05) : 1021 - 1025
  • [8] HYPERIMMUNE GLOBULINS IN PREVENTION AND TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS-INFECTIONS
    HEMMING, VG
    PRINCE, GA
    GROOTHUIS, JR
    SIBER, GR
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 1995, 8 (01) : 22 - 33
  • [9] Institute of Medicine, 1986, NEW VACC DEV EST PRI, V1, P397
  • [10] KELLOGG JA, 1991, ARCH PATHOL LAB MED, V115, P451