Modelling of the L-glutamic acid production with Corynebacterium glutamicum under biotin limitation

被引：18

作者：

Bona, R

Moser, A

机构：

[1] Technical University Graz,

[2] Institute of Biotechnology,undefined

[3] Petersgasse 12,undefined

[4] A-8010 Graz,undefined

[5] Austria,undefined

来源：

BIOPROCESS ENGINEERING | 1997年 / 17卷 / 03期

关键词：

Fermentation; Biotin; Logistic Model; Mathematical Function; Fermentation Process;

D O I：

10.1007/PL00008956

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Production of L-glutamic acid with Corynebacterium glutamicum, under biotin limitation was studied. On the base of formal kinetic approach, a mathematical model was developed, which included formal growth inhibition with product, and production repression with substrate. For the testing of computer simulations experiments were carried out and the results have been compared.

引用

页码：139 / 142

页数：4

共 7 条

[1] EVALUATION OF FEEDING STRATEGIES IN CARBON-REGULATED SECONDARY METABOLITE PRODUCTION THROUGH MATHEMATICAL-MODELING [J].

BAJPAI, RK ;

REUSS, M .

BIOTECHNOLOGY AND BIOENGINEERING, 1981, 23 (04) :717-738

[2]

BONA R, 1996, UNPUB BIOPROCESS ENG

[3]

GUILLOUET S, 1995, APPL MICROBIOL BIOT, V43, P315, DOI 10.1007/s002530050409

[4]

KRAMER R, 1994, P 6 EUR C BIOT, P595

[5]

Moser A., 1988, Bioprocess Technology: Kinetics and Reactors, V1st ed.

[6]

MOSER A, 1989, MODELLING CONTROL BI, P93

[7]

NEUBECK M, 1993, THESIS TU GRAZ

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