Modeling equilibrium clusters in lysozyme solutions

被引：112

作者：

Cardinaux, F.

Stradner, A.

Schurtenberger, P.

Sciortino, F.

Zaccarelli, E.

机构：

[1] Univ Fribourg, Dept Phys, CH-1700 Fribourg, Switzerland

[2] Univ Roma La Sapienza, Dipartimento Fis, Rome, Italy

[3] Univ Roma La Sapienza, CNR, INFM, SOFT, Rome, Italy

来源：

EPL | 2007年 / 77卷 / 04期

关键词：

D O I：

10.1209/0295-5075/77/48004

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We present a combined experimental and numerical study of the equilibrium cluster formation in globular-protein solutions under no-added salt conditions. We show that a cluster phase emerges as a result of a competition between a long-range screened Coulomb repulsion and a short-range attraction. A simple effective potential, in which electrostatic repulsion is fixed by experimental conditions and attraction is modeled with a generalized Lennard-Jones potential, accounts in a remarkable way for the wavevector dependence of the X-ray scattering structure factor.

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页数：5

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