Genotype to phenotype: challenges and opportunities

被引:13
作者
Holschneider, DP
Shih, JC
机构
[1] Univ So Calif, Sch Med, Dept Psychiat, Los Angeles, CA 90089 USA
[2] Univ So Calif, Sch Med, Dept Psychiat, Los Angeles, CA 90089 USA
[3] Univ So Calif, Sch Med, Dept Neurol, Los Angeles, CA 90033 USA
[4] Vet Adm, Greater Los Angeles Healthcare Serv, Los Angeles, CA USA
[5] Univ So Calif, Sch Med, Dept Cell & Neurobiol, Los Angeles, CA 90089 USA
[6] Univ So Calif, Sch Pharm, Dept Mol Pharmacol & Toxicol, Los Angeles, CA 90089 USA
关键词
D O I
10.1016/S0736-5748(00)00026-5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:615 / 618
页数:4
相关论文
共 25 条
[1]   Compensatory mechanism of motor defect in SOD1 transgenic mice by overactivation of striatal cholinergic neurons [J].
Azzouz, M ;
Krezel, W ;
Dollé, P ;
Vodouhe, C ;
Warter, JM ;
Poindron, P ;
Borg, J .
NEUROREPORT, 1999, 10 (05) :1013-1018
[2]   Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: Role of a serotonin excess during the critical period [J].
Cases, O ;
Vitalis, T ;
Seif, I ;
DeMaeyer, E ;
Sotelo, C ;
Gaspar, P .
NEURON, 1996, 16 (02) :297-307
[3]   Adaptive changes in postsynaptic dopamine receptors despite unaltered dopamine dynamics in mice lacking monoamine oxidase B [J].
Chen, L ;
He, M ;
Sibille, E ;
Thompson, A ;
Sarnyai, Z ;
Baker, H ;
Shippenberg, T ;
Toth, M .
JOURNAL OF NEUROCHEMISTRY, 1999, 73 (02) :647-655
[4]   AGE-DEPENDENT PENETRANCE OF DISEASE IN A TRANSGENIC MOUSE MODEL OF FAMILIAL AMYOTROPHIC-LATERAL-SCLEROSIS [J].
CHIU, AY ;
ZHAI, P ;
DALCANTO, MC ;
PETERS, TM ;
KWON, YW ;
PRATTIS, SM ;
GURNEY, ME .
MOLECULAR AND CELLULAR NEUROSCIENCE, 1995, 6 (04) :349-362
[5]   Genetics of mouse behavior: Interactions with laboratory environment [J].
Crabbe, JC ;
Wahlsten, D ;
Dudek, BC .
SCIENCE, 1999, 284 (5420) :1670-1672
[6]   A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice [J].
Crawley, JN ;
Paylor, R .
HORMONES AND BEHAVIOR, 1997, 31 (03) :197-211
[7]  
Doetschman T, 1999, LAB ANIM SCI, V49, P137
[8]   DELETION OF A DNA-POLYMERASE-BETA GENE SEGMENT IN T-CELLS USING CELL-TYPE-SPECIFIC GENE TARGETING [J].
GU, H ;
MARTH, JD ;
ORBAN, PC ;
MOSSMANN, H ;
RAJEWSKY, K .
SCIENCE, 1994, 265 (5168) :103-106
[9]   INDEPENDENT CONTROL OF IMMUNOGLOBULIN SWITCH RECOMBINATION AT INDIVIDUAL SWITCH REGIONS EVIDENCED THROUGH CRE-IOXP-MEDIATED GENE TARGETING [J].
GU, H ;
ZOU, YR ;
RAJEWSKY, K .
CELL, 1993, 73 (06) :1155-1164
[10]  
Holschneider D. P., 1999, Society for Neuroscience Abstracts, V25, P1638