An enhanced agent based model of the immune system response

被引：41

作者：

Baldazzi, V. ^{[1
]}

Castiglione, F. ^{[1
]}

Bernaschi, M. ^{[1
]}

机构：

[1] CNR, IAC, I-00161 Rome, Italy

来源：

CELLULAR IMMUNOLOGY | 2006年 / 244卷 / 02期

关键词：

computer simulation; cellular automata; HIV; HAART;

D O I：

10.1016/j.cellimm.2006.12.006

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We describe some recent enhancements introduced in C-ImmSim, a simulator of the immune system response that we have been developing for a number of years along with preliminary results produced by the simulation of the Highly Active Anti-Retroviral Therapy in HIV-1 infected patients. (c) 2007 Elsevier Inc. All rights reserved.

引用

收藏

页码：77 / 79

页数：3

相关论文

共 9 条

[1] Design and implementation of an immune system simulator [J].

Bernaschi, M ;

Castiglione, F .

COMPUTERS IN BIOLOGY AND MEDICINE, 2001, 31 (05) :303-331

[2]

BERNASCHI M, 2005, INT J MODERN PHYS C, V16

[3] Mutation, fitness, viral diversity, and predictive markers of disease progression in a computational model of HIV type 1 infection [J].

Castiglione, F ;

Poccia, F ;

D'Offizi, G ;

Bernaschi, M .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2004, 20 (12) :1314-1323

[4] A COMPUTER-MODEL OF CELLULAR INTERACTIONS IN THE IMMUNE-SYSTEM [J].

CELADA, F ;

SEIDEN, PE .

IMMUNOLOGY TODAY, 1992, 13 (02) :56-62

[5] Immunopathogenic mechanisms of HIV infection [J].

Fauci, AS ;

Pantaleo, G ;

Stanley, S ;

Weissman, D .

ANNALS OF INTERNAL MEDICINE, 1996, 124 (07) :654-663

[6] Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy [J].

Miller, MJ ;

Wei, SH ;

Cahalan, MD ;

Parker, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (05) :2604-2609

[7] Two-photon imaging of lymphocyte motility and antigen response in intact lymph node [J].

Miller, MJ ;

Wei, SH ;

Parker, I ;

Cahalan, MD .

SCIENCE, 2002, 296 (5574) :1869-1873

[8]

Munoz A, 1996, STAT MED, V15, P2459, DOI 10.1002/(SICI)1097-0258(19961130)15:22<2459::AID-SIM464>3.0.CO

[9]

2-Q