The spatial organization of cholinergic mosaics in the adult mouse retina

被引：26

作者：

Galli-Resta, L ^{[1
]}

Novelli, E ^{[1
]}

Volpini, M ^{[1
]}

Strettoi, E ^{[1
]}

机构：

[1] CNR, Ist Neurofisiol, Area Ric, I-56100 Pisa, Italy

来源：

EUROPEAN JOURNAL OF NEUROSCIENCE | 2000年 / 12卷 / 10期

关键词：

acetylcholine; amacrine cells; autocorrelation analysis; Delaunay segments;

D O I：

10.1046/j.1460-9568.2000.00280.x

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We analysed the spatial organization of the cholinergic amacrine cell mosaics in the mouse retina, as part of a general study of the major mouse retinal arrays, aiming at providing intrinsic cellular reference grids to monitor anomalies in retinal growth and/or functional organization in mouse models of retinal degeneration. The spatial organization of the cells was analysed by means of the nearest neighbour distance analysis, as well as by the analysis of Voronoi and Delaunay tesselations. We found non random cell spacing in both cholinergic arrays, although the mosaic in the ganglion cell layer tiles the retina scarcely better than a random distribution. Autocorrelation analysis revealed no detectable pattern in cell positioning, but there was a tendency towards a minimal spacing between array elements. Finally, we found no correlation in the spatial organization of the two arrays.

引用

页码：3819 / 3822

页数：4

共 21 条

[1] A GEOMETRICAL DESCRIPTION OF HORIZONTAL CELL NETWORKS IN THE TURTLE RETINA [J].