Developments in single-drop microextraction

被引:334
作者
Xu, Li [1 ]
Basheer, Chanbasha [1 ]
Lee, Hian Kee [1 ]
机构
[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
关键词
single-drop microextraction; liquid-phase microextraction; solvent-minimized extractions;
D O I
10.1016/j.chroma.2006.10.073
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Single-drop microextraction (SDME) has become a very popular liquid-phase microextraction technique because it is inexpensive, easy to operate and nearly solvent-free. Essentially, SDME combines extraction (and conceivably, cleanup) and concentration in a minimum number of steps, and thereafter, direct extract introduction into an analytical system. In this review, in order to encourage further development of SDME, we focus on its recent developments in its various guises. Its applications when used in combination with different analytical techniques, such as gas chromatography, high-performance liquid chromatography, inductively-coupled plasma mass spectrometry, capillary electrophoresis, mass spectrometry and electrothermal atomic absorption spectrometry, are summarized. SDME does have some limitations, and these are also discussed as well. Finally, an outlook on the future of the technique is given. (C) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码:184 / 192
页数:9
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