State of the art of a new functional assessment of the young nervous system. An early predictor of cerebral palsy

被引:148
作者
Prechtl, HFR [1 ]
机构
[1] Graz Univ, Dept Physiol, A-8010 Graz, Austria
关键词
qualitative assessment; general movements; spontaneous motility; fetus; newborn; young infant; central pattern generator; neurological examination;
D O I
10.1016/S0378-3782(97)00088-1
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The paper provides a survey of the state of the art of a new neurological diagnostic procedure in fetuses, preterm and term infant as well as in young infants. This method consists of a judgement of the movement quality of a particular type of spontaneous movements, the so-called general movements. At a very early age normal and abnormal general movement quality predicts the neurological outcome over 2 years, in particular cerebral palsy. The reliability of this method turned out to be very robust. Recent animal experiments on isolated parts of the central nervous system provide convincing evidence of endogenously generated neural activity. Similar neural mechanisms must provide the basis for spontaneous movements seen in the human at early ages. Those neural defects leading to qualitative changes of general movements are described in detail. (C) 1997 Elsevier Science Ireland Ltd.
引用
收藏
页码:1 / 11
页数:11
相关论文
共 58 条
[1]  
ALBERS S, 1994, BIOL NEONATE, V66, P182
[2]  
AMIELTISON C, 1983, NERUOLOGIC EVALUATIO
[3]  
[Anonymous], 1977, Clinics in Developmental Medicine
[4]   The influence of septicaemia on spontaneous motility in preterm infants [J].
Bos, AF ;
van Asperen, RM ;
de Leeuw, DM ;
Prechtl, HFR .
EARLY HUMAN DEVELOPMENT, 1997, 50 (01) :61-70
[5]   Spontaneous motility in preterm, small-for-gestational age infants - I. Quantitative aspects [J].
Bos, AF ;
van Loon, AJ ;
Martijn, A ;
van Asperen, RM ;
Okken, A ;
Prechtl, HFR .
EARLY HUMAN DEVELOPMENT, 1997, 50 (01) :115-129
[6]  
Bos AF, 1997, EARLY HUM DEV, V50, P131, DOI 10.1016/S0378-3782(97)00098-4
[7]   Spontaneous rhythmic bursts induced by pharmacological block of inhibition in lumbar motoneurons of the neonatal rat spinal cord [J].
Bracci, E ;
Ballerini, L ;
Nistri, A .
JOURNAL OF NEUROPHYSIOLOGY, 1996, 75 (02) :640-647
[8]  
CAZALETS JR, 1995, J NEUROSCI, V15, P4943
[9]   Primordial respiratory-like rhythm generation in the vertebrate embryo [J].
Champagnat, J ;
Fortin, G .
TRENDS IN NEUROSCIENCES, 1997, 20 (03) :119-124
[10]   POSITRON EMISSION TOMOGRAPHY STUDY OF HUMAN-BRAIN FUNCTIONAL-DEVELOPMENT [J].
CHUGANI, HT ;
PHELPS, ME ;
MAZZIOTTA, JC .
ANNALS OF NEUROLOGY, 1987, 22 (04) :487-497