Serotype distribution of invasive group B streptococcal isolates in infants: Results from a nationwide active laboratory surveillance study over 2 years in Germany

被引：42

作者：

Fluegge, K

Supper, S

Siedler, A

Berner, R

机构：

[1] Univ Hosp Freiburg, Dept Pediat & Adloescent Med, D-79106 Freiburg, Germany

[2] Robert Koch Inst, D-1000 Berlin, Germany

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 05期

关键词：

D O I：

10.1086/427942

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report the serotype distribution of invasive group B streptococci (GBS) isolated from 296 infants in Germany. Serotype distribution was as follows: serotype Ia, 15%; Ib, 5%; II, 5%; III, 65%; IV, 1%; and V, 8%. Analysis of serotype according to the source of isolation highlighted the considerable role of serotype III in meningitis in early-onset infection (82%) and late-onset infection (84%). Use of a trivalent GBS vaccine in Germany could theoretically provide protection against 84% and 94% of invasive early-onset and late-onset infections, respectively.

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页码：760 / 763

页数：4

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